Prescript is what healthy skin needs in just 2 products.

It may look simple, maybe too simple… but the science happens where you can’t see it.

It’s in understanding that your skin microbiome is as unique as your fingerprint. In creating personal formulations with proven active ingredients. In prescribing your unique products via a certified practitioner. In removing complexity, doubt and poor results.

Get your Prescript. Get optimally healthy skin.

Prescript is what
healthy skin needs
in just 2 products.

It may look simple, maybe too simple… but the science happens where you can’t see it.

It’s in understanding that your skin microbiome is as unique as your fingerprint.
In creating personal formulations with proven active ingredients.
In prescribing your unique products via a certified practitioner.
In removing complexity, doubt and poor results.

Get your Prescript. Get optimally healthy skin.

What is Prescript?

Every skin is unique, that’s why Esse has created Prescript – a bespoke skincare solution tailored to meet your skin’s needs. ​

Using advanced technology, your Prescript Certified Practitioner will prescribe your personalised formulation with therapeutic-grade actives by gathering essential data about your lifestyle, skincare requirements, and individual traits, through the Prescript App.​

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Complete skincare solution made for you

You only need two products to achieve a complete solution, eliminating the need for multi-step, multi-product skincare routines. Part One contains water-soluble actives, while Part Two houses oil-soluble actives. You only pay for actives that work best for your skin.

From R1500, one prescription is designed to last for an average of two months

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Why is Prescript better?

Esse Prescript

Bespoke blend of therapeutic-grade actives at optimised levels.
Formulated specifically for your skin’s needs.
A two-part unique formulation that eliminates the need for multi-step skincare routines.

Generic skincare

Non-specific active ingredient concentrations.
Caters for the average rather than the individual.
Need for numerous products to target multiple concerns.

How it works

Skin assessment

A qualified Practitioner will conduct a 15-minute skincare consultation to determine your lifestyle considerations and skin needs.

Practitioner prescribes

With the help of the Prescript App, the Practitioner will determine the tolerance levels for the applicable actives and then build an optimal, personalised skincare offering.

Prescript Lab formulates

Your prescription will then be sent to the Prescript Lab, where your crafted skincare duo will be formulated and dispensed.


Your Prescript products will be delivered to your door within 2-4 working days.


Ethics before profit

As with all Esse products, Prescript adheres to strict standards for the sustainable sourcing of both ingredients and packaging.

Find a certified Prescript Practitioner near you

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      Frequently asked questions

      Why is Prescript not organic, PETA and Vegan endorsed?

      The customisable aspect of the prescription prevents Esse from ensuring a specific combination of active ingredients that a consumer might choose to utilise. Organic certification is granted after the formulation of the product as it involves a comprehensive assessment of the entire production process. From a logical perspective, it’s reasonable to have certain active ingredients classified as organic, some as natural, all adhering to PETA suitability for cruelty-free products, and all being vegan except for pro-vitamin D. Due to the numerous potential variations in customisation, certifying each individualised product is not a practical approach.

      Is Prescript compatible with other off-the-shelf products?

      Off-the-shelf products cater to generic skin concerns with conservative doses of actives to minimise adverse reactions. In contrast, Prescript tailors’ products to your skin and its concerns, excluding unnecessary actives. This ensures that you pay only for the specific actives you skin needs.

      What is the reason for having a uniform price for all ingredients?

      We wanted to create Prescript to reach as many clients as we can, taking budget constraints into account. This is why we created a tiered system, to ensure that our Prescript clients have an equal opportunity to choose the best possible actives for their skin concerns, whilst keeping to their budget.

      Why is it not a moisturiser?

      We do not refer to these two products as replacements for a “moisturiser”. Instead, we consider them as comprehensive products that contain everything a client needs, effectively replacing all the leave-on products in their routine.

      How does Prescript differ from my current Esse products?

      While it is possible to substitute with one of Esse’s other products temporarily when one of your Prescript Parts runs out, it’s important to note that these substitutes may not provide the same targeted and customised results as the client’s individual Prescript products. The Prescript products are specifically formulated to address the client’s unique skin concerns and needs, and using alternative products may not yield the same optimal outcome. Therefore, it’s recommended to reorder the prescribed Part 1 and Part 2 in advance, allowing continued use of the personalised skincare routine. 

      Can Prescript be used around eye area?

      Prescript was designed as a whole skincare regime in two products containing all the actives you need to address your skincare concerns. Should you tend to have reactions around your eye area, we recommend applying an Esse eye product to this area instead.

      What is the shelf life, storage instructions, and recommendations for usage once Prescript is opened?

      1. Keep the products out of direct sunlight: Sunlight can cause certain ingredients in skincare products to break down and lose their efficacy. Store the products in a dark or opaque container and avoid leaving them in direct sunlight.

      2. Store in a cool environment: Heat can also degrade the potency of certain active ingredients, so it’s best to store your products in a cool and dry place.

      3. Keep the containers tightly closed: Exposure to air can lead to oxidation and spoilage of some ingredients. Ensure the containers are tightly closed after each use.  

      Can I use Prescript with other Esse products?

      Prescript products can replace additional skincare products, forming a complete routine when used with Esse.”

      Does the pricing strategy aim to target specific skin concerns without compromising product efficacy due to budget constraints?

      The cost of Prescript products is R3100, and the typical duration of use is approximately 60 days, resulting in an average daily cost of R52. Calculate your current average expenditure on skincare products and compare it to the R52 daily cost associated with Prescript.

      You can ask yourself how many times you have cappuccinos at coffee shops each week and calculate your monthly spending on them. Then, you can compare this to the monthly cost of using Prescript products.

      Can I continue with professional Esse treatments?

      Esse treatments will still be compatible with your Prescript and it can help you achieve your skincare goals. If you are due for a refill on your script, you could also have the consultation with the therapist following your professional treatment to ensure your prescription is most accurate. 

      I prefer a heavier weighted product, is it possible to achieve this outcome?

      Most certainly. You can increase the richness and nourishment of your product in each of the parts. In Part 1, you can add up to 3 shots of Humectant. Adding this will increase the thickness and add more body to the feel of your product. In Part 2, you can add more shots of Squalane. This is a slower-penetrating oil than the base product, so higher quantities of it will result in a more nourishing final product.

      Can I get it elsewhere?

      Esse provides this two-part system exclusively in South Africa. Follow link to find a practitioner near you: Practitioners

      Is it possible to place three orders? Does the system support multiple orders?

      The first order is initiated through a practitioner. Subsequently, the client has the option to place two additional reorders before returning to the practitioner for a renewed prescription. The reordering process is flexible, allowing clients to place their reorder at any point, even on the same day as their initial order.

      Is Prescript available in locations beyond South Africa?

      Currently, Prescript is not available outside South Africa.

      Is it possible to place an order for three sets of the two-part products in a single transaction?

      The Prescript system does not permit this order.

      Can I order 2 Part one/Part two?

      If one of the products runs out before the other, you have the option to purchase the depleted product separately when you reorder. However, it’s important to note that the discount is applied when you purchase two products. This could be by purchasing Part 1 and Part 2 together, or by purchasing two of either Part 1 or Part 2. If you find that you move faster through one product, you can order two of that product on your first reorder (still earning the 25% discount), and then return to ordering both parts in your next reorder.   

      Contact for further queries